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Doxycycline blocks protein creation in apicoplast (an organelle) of P. falciparum—these kinds of blocking causes two main effects: it disrupts the parasite's ability to generate fatty acids, which might be essential for its development, and it impairs the production of heme, a cofactor. These effects arise late from the parasite's lifetime cycle

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Nonetheless, while in the cells/animals that will be able to survive impaired mtCU perform, robust compensatory improvements have been present in the mtCU together with other mechanisms. Therefore, the discovery, as a result of chemical library screens on normal and mtCU-deficient cells, of recent modest-molecule inhibitors with improved mobile per

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